Synthesis and SAR of highly potent and selective dopamine D 3-receptor antagonists: 1H-Pyrimidin-2-one derivatives

H Geneste, G Backfisch, W Braje, J Delzer…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 3 p. 490 - 494

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Citation Number: 25

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... However, medical treatment of dopamine related disorders is often limited by side effects as a consequence of binding to various dopamine or other related monoamine receptors. ...