Palladium??Catalyzed Cross??Coupling of Aryl Halides Using Organotitanium Nucleophiles

…, CM So, CP Lau, ASC Chan, FY Kwong

Index: Lee, Hang Wai; Lam, Fuk Loi; So, Chau Ming; Lau, Chak Po; Chan, Albert S. C.; Kwong, Fuk Yee Angewandte Chemie, International Edition, 2009 , vol. 48, # 40 p. 7436 - 7439 Angewandte Chemie, 2009 , vol. 121, # 40 p. 7572 - 7575

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Citation Number: 35

Abstract

Palladium-catalyzed cross-coupling reactions constitute an extremely versatile protocol in organic synthesis for the connection of electrophilic to organometallic fragments through the formation of either carbon–carbon or carbon–heteroatom bonds.[1] During the past decade, enormous effort has been undertaken, especially in ligand design,[2] to enhance the capability of utilizing relatively inert electrophiles, such as aryl chlorides,[3] tosylates,[4] ...