Palladium Catalysts on Alkaline??Earth Supports for Racemization and Dynamic Kinetic Resolution of Benzylic Amines

AN Parvulescu, PA Jacobs…

Index: Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E. Chemistry - A European Journal, 2007 , vol. 13, # 7 p. 2034 - 2043

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Citation Number: 104

Abstract

Abstract Palladium catalysts on alkaline-earth supports were studied as new heterogeneous catalysts for racemization of chiral benzylic amines such as 1-phenylethylamine. Particularly 5% Pd/BaSO 4 and 5% Pd/CaCO 3 were able to selectively racemize amines, with minimal formation of secondary amines or hydrogenolysis to ethylbenzene. In contrast, these side reactions were pronounced on Pd/C. A reaction mechanism is proposed that is consistent ...