Synthesis of asymmetric 4-aryl-1, 4-dihydro-2, 6-dimethyl-3, 5-pyridinedicarboxylates with vasodilating and antihypertensive activities.

大野左千雄, 小松修, 水越清史, 市原賢二…

Index: Chemical and Pharmaceutical Bulletin, , vol. 34, # 4 p. 1589 - 1606

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Citation Number: 32

Abstract

... Chemistry The synthesis of alkyl ethylenedioxyalkyl (4) and alkyl cycloalkylmethyl 4-aryl-l,4- dihydro-2,6-dimethyl-3,S-pyridinedicarboxylate (5) were carried out by means of a modifi- cation of the Hantzsch method.4f'j'6' 2 ... Page 11. 1600 Vol. 34 (1986) TABLE XII. ...