Tetrahedron

Enantioselective synthesis of α, β-substituted β-amino acids

C Agami, S Cheramy, L Dechoux, M Melaimi

Index: Agami, Claude; Cheramy, Sandrine; Dechoux, Luc; Melaimi, Mohand Tetrahedron, 2001 , vol. 57, # 1 p. 195 - 200

Full Text: HTML

Citation Number: 20

Abstract

Chiral derivative 3 was shown to be a precursor of α and β-substituted β-amino acids as well as α, β-disubstituted β-amino acids. The key steps of the procedure are a diastereoselective alkylation of synthon 3 by organocuprates reagents and a diastereoselective alkylation of the alkylated adduct.

~65%

~61%

Enantioselective synthesis of β-amino acids. 7. Preparation ...

[Juaristi, Eusebio; Quintana, Delia; Balderas, Margarita; Garcia-Perez, Enrique Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2233 - 2246]

Synthesis of α-substituted β-amino acids using pseudoephedri...

[Organic letters, , vol. 2, # 22 p. 3527 - 3529]

Enantioselective Synthesis of β??Amino Acids, Part 13

[Gutierrez-Garcia, Victor Manuel; Reyes-Rangel, Gloria; Munoz-Muniz, Omar; Juaristi, Eusebio Helvetica Chimica Acta, 2002 , vol. 85, # 12 p. 4189 - 4199]

A new enantioselective synthesis of β-amino acids

[Saylik, Dilek; Campi, Eva M.; Donohue, Andrew C.; Jackson; Robinson, Andrea J. Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 657 - 667]

Recognition of the minor groove of DNA by hairpin polyamides...

[Gani, David; Hitchcock, Peter B.; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1363 - 1372]