Recognition of the minor groove of DNA by hairpin polyamides containing α-substituted-β-amino acids

PE Floreancig, SE Swalley, JW Trauger…

Index: Gani, David; Hitchcock, Peter B.; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1363 - 1372

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Citation Number: 61

Abstract

... solely of Py, Im, and Hp rings does not perfectly match the curvature of B-form DNA ... α-fluoro-β-alanine (13) was prepared through a variation of the sequence developed by Young and co ... this result demonstrates that the T·A/A·T binding degeneracy normally observed with the ...

~24%

~93%

Enantioselective synthesis of β-amino acids. 7. Preparation ...

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