Enantioselective synthesis of β-amino acids. 7. Preparation of enantiopure α-substituted β-amino acids from 1-benzoyl-2 (S)-tert-butyl-3-methylperhydropyrimidin-4- …

…, D Quintana, M Balderas, E García-Pérez

Index: Juaristi, Eusebio; Quintana, Delia; Balderas, Margarita; Garcia-Perez, Enrique Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2233 - 2246

Full Text: HTML

Citation Number: 103

Abstract

Inexpensive natural α-amino acid L-asparagine was efficiently converted to either (R)-or (S)- α-alkylated β-amino acids in enantiomerically pure state. The key intermediate in this protocol is the enantiopure N, N-acetal pyrimidinone (S)-1, a masked chiral derivative of β- alanine.

~80%

Synthesis of α-substituted β-amino acids using pseudoephedri...

[Organic letters, , vol. 2, # 22 p. 3527 - 3529]

Enantioselective Synthesis of β??Amino Acids, Part 13

[Gutierrez-Garcia, Victor Manuel; Reyes-Rangel, Gloria; Munoz-Muniz, Omar; Juaristi, Eusebio Helvetica Chimica Acta, 2002 , vol. 85, # 12 p. 4189 - 4199]

Enantioselective synthesis of α, β-substituted β-amino acids

[Agami, Claude; Cheramy, Sandrine; Dechoux, Luc; Melaimi, Mohand Tetrahedron, 2001 , vol. 57, # 1 p. 195 - 200]

A new enantioselective synthesis of β-amino acids

[Saylik, Dilek; Campi, Eva M.; Donohue, Andrew C.; Jackson; Robinson, Andrea J. Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 657 - 667]

Recognition of the minor groove of DNA by hairpin polyamides...

[Gani, David; Hitchcock, Peter B.; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1363 - 1372]