Synthesis of perfluorochemicals for use as blood substitutes. Part III.[1] electrochemical fluorination of quinolozidine, 4-methylquinolizidines and 4- …

Y Inoue, Y Arakawa, Y Naito, T Ono, C Fukaya…

Index: Ono, Taizo; Inoue, Yoshihisa; Arakawa, Yoshio; Naito, Youichiro; Fukaya, Chikara Journal of Fluorine Chemistry, 1989 , vol. 43, p. 67 - 86

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Citation Number: 6

Abstract

Abstract Electrochemical fluorination of quinolizidine gave F-quinolizidine in 16-23% isolated yields. 4-Methylquinolizidine was also fluorinated electrochemically to give the corresponding amine stereoisomers along with their fragmented and rearranged products in isolated yields of 28-34% and 2-3%, respectively. Introduction of an F-methyl group into the quinolizidine in place of the methyl group prior to electrochemical fluorination did not ...