Synthesis of perfluorochemicals for use as blood substitutes. Part III.[1] electrochemical fluorination of quinolozidine, 4-methylquinolizidines and 4- …
Abstract Electrochemical fluorination of quinolizidine gave F-quinolizidine in 16-23% isolated yields. 4-Methylquinolizidine was also fluorinated electrochemically to give the corresponding amine stereoisomers along with their fragmented and rearranged products in isolated yields of 28-34% and 2-3%, respectively. Introduction of an F-methyl group into the quinolizidine in place of the methyl group prior to electrochemical fluorination did not ...
