Tetrahedron letters

Formic acid as a hydride donor: Reduction of acid chlorides to aldehydes

KM Shamsuddin, MO Zobairi, MA Musharraf

Index: Shamsuddin; Zobairi, Md. Omair; Musharraf, Mohd. Asif Tetrahedron Letters, 1998 , vol. 39, # 44 p. 8153 - 8154

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Citation Number: 9

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Chlorides of a variety of acids: primary, secondary, tertiary, long chain aliphatic and αβ-unsaturated have been converted into aldehydes by reduction with formic acid at pH 9–10 at room temperature in high yields. ... Acid chlorides on reduction with formic acid yield aldehydes.

~84%

~83%

~81%

~93%

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