Synthetic Communications®

Aluminium Nitrate–Catalyzed One-Pot Synthesis of 4 (3 H)-Quinazolinones by a Three-Component Coupling of Anthranilic Acid, Amines, and Ortho Esters

M Wang, Z Song, T Zhang

Index: Wang, Min; Song, Zhiguo; Zhang, Tingting Synthetic Communications, 2011 , vol. 41, # 3 p. 385 - 391

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Citation Number: 4

Abstract

The one-pot synthesis of quinazolinone derivatives from the reaction of anthranilic acid, amines, and ortho esters in the presence of aluminium nitrate has been carried out. The reaction occurred in a few minutes at room temperature under solvent-free conditions and with excellent yield.