Chinese Chemical Letters

Strontium chloride-catalyzed one-pot synthesis of 4 (3H)-quinazolinones under solvent-free conditions

M Wang, ZG Song, TT Zhang

Index: Wang, Min; Song, Zhi Guo; Zhang, Ting Ting Chinese Chemical Letters, 2010 , vol. 21, # 10 p. 1167 - 1170

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Citation Number: 8

Abstract

The synthesis of 4(3H)-quinazolinones and their derivatives has attracted considerable attention from organic and medicinal chemists for many years because most of them showed wide pharmacological and therapeutic properties such as antimalarial, antitumor, anticonvulsant, antiinflammatory, and antimicrobial activities [1], [2], [3], [4] and [5]. In addition, 4(3H)-quinazolinones are present in several bioactive natural products [6] and [7]. Their properties turn them very interesting ...