Some Naphthalene Analogs of Desoxycorticosterone

CC Price, HI Enos Jr, W Kaplan

Index: Price; Enos; Kaplan Journal of the American Chemical Society, 1947 , vol. 69, p. 2261,2263

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Citation Number: 7

Abstract

The object of the present investigation was the preparation of simple naphthalene analogs of desoxycorticosterone, especially by conversion of 6-methoxy-1-naphthoic acid, available by condensation of anisole with furoic into hydroxymethyl ketone derivatives. Spurred by the discovery of the high estrogenic activity of synthetic analogs of estradiol and estrone, such as diethylstilbestrol and hexestrol, a number of investigators have explored the synthesis ...