Reinvestigation of the synthesis of 2-benzyl-3-aryl-quinazolin-4-[3 H]-ones. An improved multi-component procedure using microwaves

A Dandia, R Singh, P Sarawgi

Index: Dandia, Anshu; Singh, Ruby; Sarawgi, Pritima Organic Preparations and Procedures International, 2005 , vol. 37, # 4 p. 397 - 402

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Citation Number: 18

Abstract

4 [3H]-Quinazolinones have wide ranging biological activities1, 2 and have been used as anti-convulsant drugs with anti-inflammatory, analgesic and hypnotic proper tie^.^-^ Some 4 [3H]-quinazolinones also display CNS, anti-fungal, antibacterial and anti-microbial activities6.'and are also useful as anti-tumor agents. 8 2, 3-Disubstituted quinazolones have been associated with antiviral, antibacterial and antifungal acti~ ity.~ J~ An earlier ...