4 [3H]-Quinazolinones have wide ranging biological activities1, 2 and have been used as anti-convulsant drugs with anti-inflammatory, analgesic and hypnotic proper tie^.^-^ Some 4 [3H]-quinazolinones also display CNS, anti-fungal, antibacterial and anti-microbial activities6.'and are also useful as anti-tumor agents. 8 2, 3-Disubstituted quinazolones have been associated with antiviral, antibacterial and antifungal acti~ ity.~ J~ An earlier ...
[Wolfe, James F.; Rathman, Terry L.; Sleevi, Mark C.; Campbell, James A.; Greenwood, Thomas D. Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 161 - 166]