Tetrahedron

A convenient approach to the synthesis of prenyl-, furo-and pyrano-quinoline alkaloids of the rutaceae

N Shobana, P Yeshoda, P Shanmugam

Index: Shobana, N.; Yeshoda, P.; Shanmugam, P. Tetrahedron, 1989 , vol. 45, # 3 p. 757 - 762

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Citation Number: 27

Abstract

A convenient method for the synthesis of 4-hydroxy-3-prenyl-2-quinolones, which have been recognised as precursors to prenyl-,-furo-and pyranoquinoline alkaloids of the Rutaceae is described. The methodology involves C, C-diprenylation of 2, 4-dihydroxyquinoline followed by partial deallylatlon using sodium hydrogen tellurlde reagent.

~96%

~99%

~73%

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