Tetrahedron

Cooperatively assisted N-arylation using organic ionic base–Brønsted acid combination under controlled microwave heating

R Singh, BK Allam, DS Raghuvanshi, KN Singh

Index: Singh, Rahul; Allam, Bharat Kumar; Raghuvanshi, Dushyant Singh; Singh, Krishna Nand Tetrahedron, 2013 , vol. 69, # 3 p. 1038 - 1042

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Citation Number: 18

Abstract

A new synthetic strategy is developed for the construction of C–N bond through the assistance of Brønsted acid/[DBU][HOAc] without adding any metal catalyst. This is the first efficient SNAr methodology utilizing fluoro, chloro, bromo, and iodoarenes as coupling partners, which offers excellent yield up to 94% within a very short time.