Enantioselective aldol condensations. 2. Erythro-selective chiral aldol condensations via boron enolates

DA Evans, J Bartroli, TL Shih

Index: Evans, D. A.; Bartroli, J.; Shih, T. L. Journal of the American Chemical Society, 1981 , vol. 103, # 8 p. 2127 - 2129

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Citation Number: 1513

Abstract

A lb Me, CHCHO 497: l 3, 78 Sb, 69-7.9"(5.7, CHCl,) B 2b Me, CHCHO< 1: 500 4, 91 6b, 78+ 7.7"(5.4, CHCl,) C lb nC, H, CHO 141: l 3, 75 Sb, 68+ 14.9'(6.6, CH, Cl,) D 2b nC, H, CHO< 1: 500 4, 95 6b, 71-15.0"(5.0, CH, Cl,) E lb C, H CHO> 500: 1 3, 88 Sb, 81-23.1'(3.2, CHCl,) F 2b C, H CHO< l: SOO 4, 89 6b, 60+ 23.2"(3.2, CHC1,) mixture. The limits of detection by this method appear to be approximately 5OO: l. D, E, F) or chromatography (entries B, C). ...