Tetrahedron: Asymmetry

(1S, 2S)-1-Amino-2-hydroxy-1, 2, 3, 4-tetrahydronaphthalene: a new chiral auxiliary for asymmetric Reformatsky reactions

F Orsini, G Sello, AM Manzo, EM Lucci

Index: Orsini, Fulvia; Sello, Guido; Manzo, Angelo Maria; Lucci, Elvira Maria Tetrahedron Asymmetry, 2005 , vol. 16, # 11 p. 1913 - 1918

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Citation Number: 25

Abstract

(1S, 2S)-1-Amino-2-hydroxy-1, 2, 3, 4-tetrahydronaphthalene, synthesized via a chemoenzymatic approach from naphthalene, has been successfully used as a chiral auxiliary in Reformatsky-type reactions between the corresponding α- bromoacyloxazolidinone and carbonyl compounds.