Tetrahedron

Chiral acetals in organic synthesis: Regioselective synthesis of 2-and 3-hydroxy acetals from 2, 3-olefinic acetals. Reinvestigation and further applications

YD Vankar, MV Reddy, NC Chaudhuri

Index: Vankar, Yashwant D.; Reddy, M. Venkatram; Chaudhuri, Narayan C. Tetrahedron, 1994 , vol. 50, # 37 p. 11057 - 11078

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Citation Number: 5

Abstract

Achiral as well as chiral 2, 3-olefinic acetals are converted into 2-and 3-hydroxy acetals via LAH reduction of the corresponding epoxides and via bromohydrins followed by TBTH reductions respectively. Synthesis of 1, 3-diones is described. Compounds from chiral systems are further utilized for asymmetric synthesis.