The Journal of Organic Chemistry

Electrochemistry of natural products. 7. Oxidative decarboxylation of some tetrahydro-. beta.-carbolinecarboxylic acids

JM Bobbitt, JP Willis

Index: Bobbitt, James M.; Willis, John P. Journal of Organic Chemistry, 1980 , vol. 45, # 10 p. 1978 - 1984

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Citation Number: 54

Abstract

6 k2\,-cop years ago by Jacobs and Craig6 and Robinson.'If the 3-carboxyl group is retained through the ring-closure reaction, the crucial question becomes whether it can be easily removed or not. The second point of variation hinges upon whether acetaldehyde or pyruvic acid is the ring-closure reagent for the formation of the@-carboline ring. Both reagents react readily under “physiological conditions” to give the ring system, but it has long been ...