KC7F2

更新时间：2024-01-03 17:51:11

KC7F2结构式	常用名	KC7F2	英文名	KC7F2
	CAS号	927822-86-4	分子量	570.381
	密度	1.6±0.1 g/cm3	沸点	708.8±70.0 °C at 760 mmHg
	分子式	C₁₆H₁₆Cl₄N₂O₄S₄	熔点	N/A
	MSDS	中文版美版	闪点	382.5±35.7 °C

KC7F2用途

KC7F2是一种有效的HIF-1途径抑制剂,可用作癌症治疗剂。

中文名	KC7F2
英文名	2,5-dichloro-N-[2-[2-[(2,5-dichlorophenyl)sulfonylamino]ethyldisulfanyl]ethyl]benzenesulfonamide
英文别名	更多

描述	KC7F2是一种有效的HIF-1途径抑制剂,可用作癌症治疗剂。
相关类别	信号通路 >> 代谢酶/蛋白酶 >> HIF/HIF脯氨酰-羟化酶研究领域 >> 癌症
参考文献	[1]. Narita T, et al. Identification of a novel small molecule HIF-1alpha translation inhibitor. Clin Cancer Res. 2009 Oct 1;15(19):6128-6136. [2]. Koh MY, et al. Inhibiting the hypoxia response for cancer therapy: the new kid on the block. Clin Cancer Res. 2009 Oct 1;15(19):5945-5946.

描述

KC7F2是一种有效的HIF-1途径抑制剂,可用作癌症治疗剂。

相关类别

信号通路 >> 代谢酶/蛋白酶 >> HIF/HIF脯氨酰-羟化酶

研究领域 >> 癌症

参考文献

[1]. Narita T, et al. Identification of a novel small molecule HIF-1alpha translation inhibitor. Clin Cancer Res. 2009 Oct 1;15(19):6128-6136.

[2]. Koh MY, et al. Inhibiting the hypoxia response for cancer therapy: the new kid on the block. Clin Cancer Res. 2009 Oct 1;15(19):5945-5946.

密度	1.6±0.1 g/cm3
沸点	708.8±70.0 °C at 760 mmHg
分子式	C₁₆H₁₆Cl₄N₂O₄S₄
分子量	570.381
闪点	382.5±35.7 °C
精确质量	567.874695
PSA	159.70000
LogP	6.39
外观性状	white solid
蒸汽压	0.0±2.3 mmHg at 25°C
折射率	1.643
储存条件	-20℃

KC7F2MSDS英文版

危险品运输编码	NONH for all modes of transport

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Oct-3/4 promotes tumor angiogenesis through VEGF production in glioblastoma.

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Lenticular cytoprotection. Part 1: the role of hypoxia inducible factors-1α and -2α and vascular endothelial growth factor in lens epithelial cell survival in hypoxia.

Mol. Vis. 19 , 1-15, (2013)

The prosurvival signaling cascades that mediate the unique ability of human lens epithelial cells to survive in their naturally hypoxic environment are not well defined. Hypoxia induces the synthesis ...

Benzenesulfonamide, N,N'-(dithiodi-2,1-ethanediyl)bis[2,5-dichloro-

UNII-94C2DMM81L

N,N'-(Disulfanediyldi-2,1-ethanediyl)bis(2,5-dichlorobenzenesulfonamide)

KC7f2

N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide