降钙素基因相关肽,人

更新时间：2025-09-08 12:00:14

降钙素基因相关肽,人结构式	常用名	降钙素基因相关肽,人	英文名	α-CGRP (human) trifluoroacetate salt
	CAS号	90954-53-3	分子量	3789.31
	密度	N/A	沸点	N/A
	分子式	C₁₆₃H₂₆₇N₅₁O₄₉S₂	熔点	N/A
	MSDS	美版	闪点	N/A

降钙素基因相关肽,人用途

α-CGRP(human) 是一种含有 37 个氨基酸的调节性神经肽,广泛分布于中枢神经系统和周围神经系统。α-CGRP(human) 是一种有效的血管扩张药。

中文名	人类降钙素基因相关肽 1
英文名	2-[(4R,7S,10S,13S,16S,19R)-4-[[(1S)-1-[[(1S,2R)-1-[[(1S)-2-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[2-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-1-[[(1S)-2-[[2-[[2-[[(1S)-1-[[(1S)-1-[[(1S)-5-amino-1-[[(1S)-3-amino-1-[[(1S)-3-amino-1-[[(1S)-2-[[(1S)-1-[(2S)-2-[[(1S,2R)-1-[[(1S)-3-amino-1-[[(1S)-1-[[2-[[(1S)-2-[[(1S)-5-amino-1-[[(1S)-2-[[(1S)-2-amino-1-benzyl-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]pentyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]carbamoyl]-3-oxo-propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]amino]-1-benzyl-2-oxo-ethyl]carbamoyl]-3-oxo-propyl]carbamoyl]-3-oxo-propyl]carbamoyl]pentyl]carbamoyl]-2-methyl-propyl]carbamoyl]-2-methyl-propyl]amino]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-4-guanidino-butyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]-2-methyl-propyl]carbamoyl]-19-[[(2S)-2-aminopropanoyl]amino]-7,13-bis[(1R)-1-hydroxyethyl]-10-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-16-yl]acetic acid
英文别名	更多

描述	α-CGRP(human) 是一种含有 37 个氨基酸的调节性神经肽,广泛分布于中枢神经系统和周围神经系统。α-CGRP(human) 是一种有效的血管扩张药。
相关类别	研究领域 >> 心血管疾病信号通路 >> 其他 >> 其他
参考文献	[1]. Ambrish Kumar, et al. Protective Role of α-Calcitonin Gene-Related Peptide in Cardiovascular Diseases. Front Physiol. 2019 Jul 2;10:821.

分子式	C₁₆₃H₂₆₇N₅₁O₄₉S₂
分子量	3789.31
InChIKey	DNKYDHSONDSTNJ-XJVRLEFXSA-N
SMILES	CC(C)CC(NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(NC(=O)C(NC(=O)C(CS)NC(=O)C(NC(=O)C(C)NC(=O)C(NC(=O)C(CC(=O)O)NC(=O)C(CS)NC(=O)C(C)N)C(C)O)C(C)O)C(C)C)C(C)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(N)=O)C(C)C)C(C)O)C(C)C)C(C)C)C(C)C
储存条件	-20°C

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危害码 (欧洲)	Xi
危险品运输编码	NONH for all modes of transport
WGK德国	3.0

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Mol. Cell. Endocrinol. 403 , 78-87, (2015)

Stanniocalcin 1 (STC1) and calcitonin gene-related peptide (CGRP) are involved in bone formation/remodeling. Here we investigate the effects of STC1 on functional heterodimer complex CALCRL/RAMP1, exp...

Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip.

Arthritis. Res. Ther. 17(1) , 4, (2015)

Developmental dysplasia of the hip (DDH) is a common musculoskeletal disorder that has pain and loss of joint function as major pathological features. In the present study, we explored the mechanisms ...

The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant.

Mol. Pain 4 , 61, (2008)

The present study aims to investigate the role of transient receptor potential vanilloid 1 (TRPV1) in dorsal root ganglion (DRG) neurons in chronic pain including thermal hyperalgesia and mechanical a...

Human calcitonin gene-related peptide 1

alpha-Calcitonin gene-related peptide (human)

β-CGRP (human)