氟铃脲

常用名 氟铃脲 英文名 hexaflumuron
CAS号 86479-06-3 分子量 461.143
密度 1.6±0.1 g/cm3 沸点 N/A
分子式 C16H8Cl2F6N2O3 熔点 202-205ºC
MSDS氟铃脲的MSDS|SDS|pdf下载 中文版 美版 闪点 N/A
符号 GHS07 GHS09
GHS07, GHS09
信号词 Warning

 氟铃脲用途


苯甲酰脲类昆虫生长调节剂,具有很高的杀虫和杀卵活性,杀虫谱较广。其作用机理是抑制几丁质形成,阻碍害虫正常蜕皮和变态,还能抑制害虫进食速度。可防治棉花、果树上的鞘翅目、鳞翅目、双翅目、同翅目害虫,兼有杀卵活性。尤其对棉铃虫等害虫效果很好,对螨无效。


 氟铃脲物理化学性质

[ 密度 ]: 1.6±0.1 g/cm3
[ 熔点 ]: 202-205ºC
[ 分子式 ]: C16H8Cl2F6N2O3
[ 分子量 ]: 461.143
[ 精确质量 ]: 459.981628
[ PSA ]: 67.43000
[ LogP ]: 5.87
[ 外观性状 ]: 无色固体或白色粉末
[ 折射率 ]: 1.548
[ 分子结构 ]:

1、 摩尔折射率:90.75

2、 摩尔体积(cm3/mol):285.7

3、 等张比容(90.2K):732.6

4、 表面张力(dyne/cm):43.1

5、 极化率(10-24cm3):35.97

[ 计算化学 ]:

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:2

3.氢键受体数量:9

4.可旋转化学键数量:5

5.互变异构体数量:5

6.拓扑分子极性表面积67.4

7.重原子数量:29

8.表面电荷:0

9.复杂度:581

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

[ 更多 ]:

1.性状:纯品为白色结晶

2.相对密度:1.68

3.熔点(ºC):197~199

4.溶解性:溶于丙酮、二氯甲烷。化学性质稳定。

 氟铃脲毒性和生态

氟铃脲毒理学数据:

鼠急性经口 LD50>5000mg/kg,小鼠 LD50>2000mg/kg;大鼠急性经皮 LD50>2000mg/kg(>5000mg/kg);大鼠急性吸入 LC50>2.5mg/L (4h)。大鼠2年喂养无作用剂量为每天75mg/kg,狗1年喂养无作用剂量为每天0.5mg/kg。皮肤致敏试验阴性。动物试验未见致畸、致突变作用。虹鳟鱼LC50>32×10-9 (96h)。蜜蜂经口LD50为0.1mg/只;对家蚕、鱼类毒性大。

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV3800000
CHEMICAL NAME :
Benzamide, N-(((3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl )amino)carbonyl)-2,6- difluoro-
CAS REGISTRY NUMBER :
86479-06-3
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C16-H18-Cl2-F6-N2-O3
MOLECULAR WEIGHT :
471.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,471,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2500 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,471,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,471,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,471,1991

 氟铃脲安全信息

[ 符号 ]: GHS07 GHS09
GHS07, GHS09
[ 信号词 ]: Warning
[ 危害声明 ]: H332-H410
[ 警示性声明 ]: P273-P501
[ 个人防护装备 ]: Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危害码 (欧洲) ]: N:Dangerousfortheenvironment;
[ 风险声明 (欧洲) ]: R50/53
[ 安全声明 (欧洲) ]: S60-S61
[ 危险品运输编码 ]: UN 3077
[ RTECS号 ]: CV3800000
[ 包装等级 ]: III
[ 危险类别 ]: 9

 氟铃脲制备

3,5-二氯-4-(1,1,2,2-四氟乙氧基)苯胺与光气(或草酰氯)作用,使氨基转化为异氰酸基,制得3,5-二氯-4-(1,1,2,2-四氟乙氧基)苯基异氰酸酯,然后再与2,6-二氟苯甲酰胺作用

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