Hygrolidin

• 常用名: Hygrolidin
• 英文名: Antibiotic 1166C
• CAS号: 83329-73-1
• 分子量: 690.86100
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₈H₅₈O₁₁
• 熔点: N/A
• 闪点: N/A

Hygrolidin用途

Hygrolidin is a macrocyclic lactone that inhibits proliferation of DLD-1 colon cancer, LNCaP prostate cancer, and K562 leukemia cells. Hygrolidin induces the expression and levels of p21 in DLD-1 cells, but not WI-38 fibroblasts, and leads to cell accumulation in the G1 and S phases without inducing apoptosis. It has antiparasitic activity against T. cruzi, L. donovani, and T. b. brucei but also induces cytotoxicity in HepG2 cells.

Hygrolidin名称

• 英文名: hygrolidin

Hygrolidin物理化学性质

• 分子式: C₃₈H₅₈O₁₁
• 分子量: 690.86100
• 精确质量: 690.39800
• PSA: 169.05000
• LogP: 5.05440