norbuprenorphine结构式
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常用名 | norbuprenorphine | 英文名 | norbuprenorphine |
|---|---|---|---|---|
| CAS号 | 78715-23-8 | 分子量 | 413.55000 | |
| 密度 | 1.27g/cm3 | 沸点 | 562.7ºC at 760 mmHg | |
| 分子式 | C25H35NO4 | 熔点 | 221-224ºC | |
| MSDS | N/A | 闪点 | 294.1ºC | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
| 英文名 | norbuprenorphine |
|---|---|
| 英文别名 | 更多 |
| 密度 | 1.27g/cm3 |
|---|---|
| 沸点 | 562.7ºC at 760 mmHg |
| 熔点 | 221-224ºC |
| 分子式 | C25H35NO4 |
| 分子量 | 413.55000 |
| 闪点 | 294.1ºC |
| 精确质量 | 413.25700 |
| PSA | 70.95000 |
| LogP | 3.62020 |
| 折射率 | 1.627 |
| 符号 |
GHS02, GHS06, GHS08 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H225-H301 + H311 + H331-H370 |
| 警示性声明 | P210-P260-P280-P301 + P310-P311 |
| 危险品运输编码 | UN1230 - class 3 - PG 2 - Methanol, solution |
| norbuprenorphine上游产品 2 | |
|---|---|
| norbuprenorphine下游产品 1 | |
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P-glycoprotein is a major determinant of norbuprenorphine brain exposure and antinociception.
J. Pharmacol. Exp. Ther. 343(1) , 53-61, (2012) Norbuprenorphine is a major metabolite of buprenorphine and potent agonist of μ, δ, and κ opioid receptors. Compared with buprenorphine, norbuprenorphine causes minimal antinociception but greater res... |
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Chemical and enzyme-assisted syntheses of norbuprenorphine-3-β-D-glucuronide.
Bioconjug. Chem. 22(4) , 752-8, (2011) Norbuprenorphine-3-β-d-glucuronide (nBPN-3-β-d-G, 1) is a major phase II metabolite of buprenorphine, a pharmaceutical used for the treatment of opioid addiction. The pharmacological activity of compo... |
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Preliminary buprenorphine sublingual tablet pharmacokinetic data in plasma, oral fluid, and sweat during treatment of opioid-dependent pregnant women.
Ther. Drug Monit. 33(5) , 619-26, (2011) Buprenorphine is currently under investigation as a pharmacotherapy to treat pregnant women for opioid dependence. This research evaluates buprenorphine (BUP), norbuprenophine (NBUP), buprenorphine-gl... |
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CAS号52485-79-7