78715-23-8

• 常用中文名：norbuprenorphine
• 常用英文名：norbuprenorphine
• CAS号：78715-23-8
• 分子式：C₂₅H₃₅NO₄
• 分子量：413.55000
• 发布时间：2017-08-04 16:17:19
• 更新时间：2025-08-24 09:15:53

名称

• 英文名: norbuprenorphine
• 英文别名: 6-Methylamino-4,4-diphenyl-3-heptanol-acetat; 7a-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydronororipavine; Noracetylmethadol; paracymethadol; Noracetylmethadone; Noracymethadole

物化性质

• 密度: 1.27g/cm3
• 沸点: 562.7ºC at 760 mmHg
• 熔点: 221-224ºC
• 分子式: C₂₅H₃₅NO₄
• 分子量: 413.55000
• 闪点: 294.1ºC
• 精确质量: 413.25700
• PSA: 70.95000
• LogP: 3.62020
• 折射率: 1.627

安全

• 符号: GHS02, GHS06, GHS08
• 信号词: Danger
• 危害声明: H225-H301 + H311 + H331-H370
• 警示性声明: P210-P260-P280-P301 + P310-P311
• 危险品运输编码: UN1230 - class 3 - PG 2 - Methanol, solution

合成路线

22151-78-6 ~80% 78715-23-8

文献：MALLINCKRODT INC.; ALLEN, Brenda, E.; JARVI, Esa, T.; KALOTA, Dennis, J.; MEYER, James, R.; TOMAZI, Keith, G.; MANNINO, Anthony; ORR, Brian Patent: WO2010/39220 A1, 2010 ; Location in patent: Page/Page column 30-31 ;

22152-80-3 ~16% 22151-78-6 78715-23-8

文献：RECKITT BENCKISER HEALTHCARE (UK) LIMITED Patent: WO2003/95458 A1, 2003 ; Location in patent: Page/Page column 10; 11 ;

1352741-85-5 ~41% 1352741-86-6 78715-23-8

文献：MacHara, Ales; Werner, Lukas; Endoma-Arias, Mary Ann; Cox, D. Phillip; Hudlicky, Tomas Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 613 - 626

1352741-85-5 ~35% 1352741-86-6 22151-78-6 78715-23-8

文献：MacHara, Ales; Werner, Lukas; Endoma-Arias, Mary Ann; Cox, D. Phillip; Hudlicky, Tomas Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 613 - 626

1352741-86-6 ~% 78715-23-8

文献：MacHara, Ales; Werner, Lukas; Endoma-Arias, Mary Ann; Cox, D. Phillip; Hudlicky, Tomas Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 613 - 626

22152-80-3 ~% 78715-23-8

文献：MacHara, Ales; Werner, Lukas; Endoma-Arias, Mary Ann; Cox, D. Phillip; Hudlicky, Tomas Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 613 - 626

1352741-85-5 ~% 78715-23-8

文献：MacHara, Ales; Werner, Lukas; Endoma-Arias, Mary Ann; Cox, D. Phillip; Hudlicky, Tomas Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 613 - 626

上下游产品

上游产品  2
22151-78-6 1352741-85-5
下游产品  1
52485-79-7