(E)-10-Hydroxynortriptyline

更新时间：2024-01-18 22:37:48

(E)-10-Hydroxynortriptyline结构式	常用名	(E)-10-Hydroxynortriptyline	英文名	(E)-10-Hydroxynortriptyline
	CAS号	47132-16-1	分子量	279.37600
	密度	1.164g/cm3	沸点	462.3ºC at 760mmHg
	分子式	C₁₉H₂₁NO	熔点	N/A
	MSDS	N/A	闪点	142.1ºC

(E)-10-Hydroxynortriptyline用途

(E)-10-Hydroxynortriptyline (E-10-OH-NT) 是 Nortriptyline (HY-B1417) 的代谢物。Nortriptyline 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢物,用于缓解抑郁症状。

英文名	()-trans-10-hydroxynortriptyline
英文别名	更多

描述

(E)-10-Hydroxynortriptyline (E-10-OH-NT) 是 Nortriptyline (HY-B1417) 的代谢物。Nortriptyline 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢物,用于缓解抑郁症状。

相关类别

研究领域 >> 神经疾病

参考文献

[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

[2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.

密度	1.164g/cm3
沸点	462.3ºC at 760mmHg
分子式	C₁₉H₂₁NO
分子量	279.37600
闪点	142.1ºC
精确质量	279.16200
PSA	32.26000
LogP	3.70820

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(E)-10-Hydroxynortriptyline上游产品 8
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(E)-10-Hydroxynortriptyline下游产品 0

E-10-hydroxynortriptyline

trans-10-Hydroxy Nortriptyline Maleate