(E)-10-Hydroxy Nortriptyline maleate

• 常用名: (E)-10-Hydroxy Nortriptyline maleate
• 英文名: (E)-10-Hydroxy Nortriptyline maleate
• CAS号: 74853-74-0
• 分子量: 395.44800
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₅NO₅
• 熔点: N/A
• 闪点: N/A

(E)-10-Hydroxy Nortriptyline maleate用途

(E)-10-Hydroxy Nortriptyline maleate 是 Nortriptyline 的代谢物。Nortriptyline 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢物,用于缓解抑郁症状。

(E)-10-Hydroxy Nortriptyline maleate名称

• 中文名: 反式-10-羟基去甲替林
• 英文名: (Z)-but-2-enedioic acid,(11E)-11-[3-(methylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol

(E)-10-Hydroxy Nortriptyline maleate生物活性

• 描述: (E)-10-Hydroxy Nortriptyline maleate 是 Nortriptyline 的代谢物。Nortriptyline 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢物,用于缓解抑郁症状。
• 相关类别:
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

  [2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.

(E)-10-Hydroxy Nortriptyline maleate物理化学性质

• 分子式: C₂₃H₂₅NO₅
• 分子量: 395.44800
• 精确质量: 395.17300
• PSA: 106.86000
• LogP: 3.42000

(E)-10-Hydroxy Nortriptyline maleate英文别名

• trans-10-Hydroxy Nortriptyline Maleate