Desmethylnortriptyline

• 常用名: Desmethylnortriptyline
• 英文名: Desmethylnortriptyline
• CAS号: 4444-42-2
• 分子量: 249.35000
• 密度: 1.127g/cm3
• 沸点: 399.2ºC at 760 mmHg
• 分子式: C₁₈H₁₉N
• 熔点: N/A
• 闪点: 191.8ºC

Desmethylnortriptyline用途

Desmethylnortriptyline 是 Nortriptyline 的代谢产物。Nortriptyline 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢产物,用于缓解抑郁症症状。

Desmethylnortriptyline名称

• 英文名: 3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)propan-1-amine

Desmethylnortriptyline生物活性

• 描述: Desmethylnortriptyline 是 Nortriptyline 的代谢产物。Nortriptyline 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢产物,用于缓解抑郁症症状。
• 相关类别:
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Burch JE, et al. Determination of desmethyl nortriptyline in plasma by gas chromatography before and after treatment with salicylaldehyde. J Chromatogr. 1983 May 13;274:350-4.

  [2]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

Desmethylnortriptyline物理化学性质

• 密度: 1.127g/cm3
• 沸点: 399.2ºC at 760 mmHg
• 分子式: C₁₈H₁₉N
• 分子量: 249.35000
• 闪点: 191.8ºC
• 精确质量: 249.15200
• PSA: 26.02000
• LogP: 4.26600
• InChIKey: PTQFRALDEONNOA-UHFFFAOYSA-N
• SMILES: NCCC=C1c2ccccc2CCc2ccccc21
• 折射率: 1.664

Desmethylnortriptyline安全信息

• 海关编码: 2921499090

Desmethylnortriptyline海关

• 海关编码: 2921499090
• 中文概述: 2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Desmethylnortriptyline英文别名

• Desmethylnortriptyline
• N-desmethyl-nortriptyline
• didesmethylamitriptyline
• 5-<3-Amino-propyliden>-10,11-dihydro-5H-dibenzo<a,d>cyclohepten