伊必那班结构式
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常用名 | 伊必那班 | 英文名 | (S)-SLV 319 |
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CAS号 | 464213-10-3 | 分子量 | 487.401 | |
密度 | 1.4±0.1 g/cm3 | 沸点 | 623.2±65.0 °C at 760 mmHg | |
分子式 | C23H20Cl2N4O2S | 熔点 | N/A | |
MSDS | N/A | 闪点 | 330.7±34.3 °C |
伊必那班用途Ibipinabant, also known as BMS-646256, JD-5001 and SLV-319, is a potent and highly selective CB1 antagonist. It has potent anorectic effects in animals, and was researched for the treatment of obesity, although CB1 antagonists as a class have now fallen out of favour as potential anorectics following the problems seen with rimonabant, and so ibipinabant is now only used for laboratory research, especially structure-activity relationship studies into novel CB1 antagonists. |
中文名 | 伊必那班 |
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英文名 | (4S)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide |
中文别名 | (4S)-3-(4-氯苯基)-N-[(4-氯苯基)磺酰基]-4,5-二氢-N'-甲基-4-苯基-1H-吡唑-1-甲脒 |
英文别名 | 更多 |
密度 | 1.4±0.1 g/cm3 |
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沸点 | 623.2±65.0 °C at 760 mmHg |
分子式 | C23H20Cl2N4O2S |
分子量 | 487.401 |
闪点 | 330.7±34.3 °C |
精确质量 | 486.068390 |
PSA | 82.51000 |
LogP | 4.67 |
蒸汽压 | 0.0±1.8 mmHg at 25°C |
折射率 | 1.663 |
1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N'-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N-methyl-4-phenyl-, (4S)- |
UNII-O5CSC6WH1T |
(4S)-3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-N'-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide |
ibipinabant |
1H-pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4S)- |