(S)-Butaprost free acid

• 常用名: (S)-Butaprost free acid
• 英文名: (S)-Butaprost free acid
• CAS号: 433219-55-7
• 分子量: 394.545
• 密度: 1.1±0.1 g/cm3
• 沸点: 565.7±50.0 °C at 760 mmHg
• 分子式: C₂₃H₃₈O₅
• 熔点: N/A
• 闪点: 310.0±26.6 °C

(S)-Butaprost free acid用途

(S) -Butaprost(游离酸)是一种有效且高度选择性的EP2受体激动剂[1]。

(S)-Butaprost free acid名称

• 英文名: (+/-)-15-deoxy-16r-hydroxy-17-cyclobutyl prostaglandin e1

(S)-Butaprost free acid生物活性

• 描述: (S) -Butaprost(游离酸)是一种有效且高度选择性的EP2受体激动剂[1]。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体
• 靶点:

  EP2[1]

• 参考文献:

  [1]. Tani K, et al. Development of a highly selective EP2-receptor agonist. Part 2: identification of 16-hydroxy-17,17-trimethylene 9beta-chloro PGF derivatives. Bioorg Med Chem. 2002;10(4):1107-1114.

(S)-Butaprost free acid物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 565.7±50.0 °C at 760 mmHg
• 分子式: C₂₃H₃₈O₅
• 分子量: 394.545
• 闪点: 310.0±26.6 °C
• 精确质量: 394.271912
• PSA: 94.83000
• LogP: 3.04
• 蒸汽压: 0.0±3.5 mmHg at 25°C
• 折射率: 1.558

(S)-Butaprost free acid英文别名

• 17,20-Cycloprost-13-en-1-oic acid, 11,16-dihydroxy-9-oxo-17-propyl-, (11α,13E,16S)-
• 17,20-Cycloprost-13-en-1-oic acid, 11,16-dihydroxy-9-oxo-17-propyl-, (11α,13E,16R)-
• 9-oxo-11alpha,16s-dihydroxy-17-cyclobutyl-prost-13e-en-1-oic acid
• Cyclopentaneheptanoic acid, 3-hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-buten-1-yl]-5-oxo-, (1R,2R,3R)-
• 9-oxo-11alpha,16r-dihydroxy-17-cyclobutyl-prost-13e-en-1-oic acid
• 7-{(1R,2R,3R)-3-Hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-buten-1-yl]-5-oxocyclopentyl}heptanoic acid
• (11α,13E,16S)-11,16-Dihydroxy-9-oxo-17-propyl-17,20-cycloprost-13-en-1-oic acid
• (11α,13E,16R)-11,16-Dihydroxy-9-oxo-17-propyl-17,20-cycloprost-13-en-1-oic acid