N6-环戊基腺苷酸结构式
|
常用名 | N6-环戊基腺苷酸 | 英文名 | N6-Cyclopentyladenosine |
|---|---|---|---|---|
| CAS号 | 41552-82-3 | 分子量 | 335.36 | |
| 密度 | 1.78g/cm3 | 沸点 | 673.4ºC at 760 mmHg | |
| 分子式 | C15H21N5O4 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 361.1ºC |
N6-环戊基腺苷酸用途N6-Cyclopentyladenosine (CPA) 是一个选择性的腺苷A1 受体 (Adenosine A1 receptor)的激动剂，其对人A1、A2A 和 A3 受体的Ki 分别为 2.3 nM、790 nM 和 43 nM。 |
| 中文名 | N6-环戊基腺苷酸 |
|---|---|
| 英文名 | (2R,3R,4S,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
| 中文别名 | N6-环戊基TYLADENOSINE |
| 英文别名 | 更多 |
| 描述 | N6-Cyclopentyladenosine (CPA) 是一个选择性的腺苷A3 受体 (Adenosine A1 receptor)的激动剂,其对人A1、A2A 和 A3 受体的Ki 分别为 2.3 nM、790 nM 和 43 nM。 |
|---|---|
| 相关类别 | |
| 靶点 |
Ki: 2.3 nM (A1), 790 nM (A2A), 43 nM(A3)[1]. |
| 参考文献 |
| 密度 | 1.78g/cm3 |
|---|---|
| 沸点 | 673.4ºC at 760 mmHg |
| 分子式 | C15H21N5O4 |
| 分子量 | 335.36 |
| 闪点 | 361.1ºC |
| 精确质量 | 335.15900 |
| PSA | 125.55000 |
| 折射率 | 1.816 |
| 储存条件 | 2-8℃ |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
|
~79%
N6-环戊基腺苷酸 41552-82-3 |
| 文献：Ottria, Roberta; Casati, Silvana; Baldoli, Erika; Maier, Jeanette A.M.; Ciuffreda, Pierangela Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 23 p. 8396 - 8402 |
|
~70%
N6-环戊基腺苷酸 41552-82-3 |
| 文献：Vittori, Sauro; Lorenzen, Anna; Stannek, Christina; Costanzi, Stefano; Volpini, Rosaria; Ijzerman, Adriaan P.; Von Frijtag Drabbe Kunzel, Jakobien K.; Cristalli, Gloria Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 250 - 260 |
|
~85%
N6-环戊基腺苷酸 41552-82-3 |
| 文献：Fletcher, Steven Tetrahedron Letters, 2010 , vol. 51, # 22 p. 2948 - 2950 |
|
~%
N6-环戊基腺苷酸 41552-82-3 |
| 文献：Vittori, Sauro; Lorenzen, Anna; Stannek, Christina; Costanzi, Stefano; Volpini, Rosaria; Ijzerman, Adriaan P.; Von Frijtag Drabbe Kunzel, Jakobien K.; Cristalli, Gloria Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 250 - 260 |
|
~%
N6-环戊基腺苷酸 41552-82-3 |
| 文献：Vittori, Sauro; Lorenzen, Anna; Stannek, Christina; Costanzi, Stefano; Volpini, Rosaria; Ijzerman, Adriaan P.; Von Frijtag Drabbe Kunzel, Jakobien K.; Cristalli, Gloria Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 250 - 260 |
|
~%
N6-环戊基腺苷酸 41552-82-3 |
| 文献：Inotek Pharmaceuticals Corporation Patent: US2007/238694 A1, 2007 ; Location in patent: Page/Page column 130 ; |
| N6-环戊基腺苷酸上游产品 5 | |
|---|---|
| N6-环戊基腺苷酸下游产品 0 | |
|
The effect of pH and ion channel modulators on human placental arteries.
PLoS ONE 9(12) , e114405, (2014) Chorionic plate arteries (CPA) are located at the maternofetal interface where they are able to respond to local metabolic changes. Unlike many other types of vasculature, the placenta lacks nervous c... |
|
|
Acid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium.
Arthritis. Res. Ther. 16(3) , R121, (2014) Acid-sensing ion channel 3 (ASIC3) is expressed in synoviocytes, activated by decreases in pH, and reduces inflammation in animal models of inflammatory arthritis. The purpose of the current study was... |
|
|
Chemoenzymatic Syntheses of Sialylated Oligosaccharides Containing C5-Modified Neuraminic Acids for Dual Inhibition of Hemagglutinins and Neuraminidases.
Chemistry 21 , 10903-12, (2015) A fast chemoenzymatic synthesis of sialylated oligosaccharides containing C5-modified neuraminic acids is reported. Analogues of GM3 and GM2 ganglioside saccharidic portions where the acetyl group of ... |
| N6-Cyclopentyladenosine |
查看所有供应商和价格请点击：
![9-[2,3,5-三-O-乙酰基-β-D-呋喃核糖基] -2,6-二氯结构式](https://www.chemsrc.com/caspic/019/3056-18-6.png)
