Bicyclopyrone

• 常用名: Bicyclopyrone
• 英文名: Bicyclopyrone
• CAS号: 352010-68-5
• 分子量: 399.36
• 密度: 1.387g/cm3
• 沸点: 489.521ºC at 760 mmHg
• 分子式: C₁₉H₂₀F₃NO₅
• 熔点: N/A
• 闪点: 249.853ºC

Bicyclopyrone用途

双环吡喃酮是4-羟基苯丙酮酸双加氧酶(Hpd)的抑制剂[1]。

Bicyclopyrone名称

• 中文名: 氟吡草酮
• 英文名: bicyclopyrone

Bicyclopyrone生物活性

• 描述: 双环吡喃酮是4-羟基苯丙酮酸双加氧酶(Hpd)的抑制剂[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 体外研究: 4-羟基苯丙酮酸双加氧酶催化4-羟基苯丙酮酸转化为高龙胆酸是黑色素生物合成途径的最后一步[1]。
• 参考文献:

  [1]. María Elisa Pavan, et al. Glycerol inhibition of melanin biosynthesis in the environmental Aeromonas salmonicida 34mel T. Appl Microbiol Biotechnol. 2019 Feb;103(4):1865-1876.

Bicyclopyrone物理化学性质

• 密度: 1.387g/cm3
• 沸点: 489.521ºC at 760 mmHg
• 分子式: C₁₉H₂₀F₃NO₅
• 分子量: 399.36
• 闪点: 249.853ºC
• 精确质量: 399.12900
• PSA: 85.72000
• LogP: 3.25720
• InChIKey: AIAYSXFWIUNXRC-PHIMTYICSA-N
• SMILES: COCCOCc1nc(C(F)(F)F)ccc1C(O)=C1C(=O)C2CCC(C2)C1=O
• 折射率: 1.547
• 储存条件: -20°C，干燥，密封

Bicyclopyrone安全信息

• 危害码 (欧洲): Xi

Bicyclopyrone英文别名

• 4-Hydroxy-3-[2-(2-methoxyethoxymethyl)-6-trifluoromethylpyridine-3-carbonyl]-bicyclo[3.2.1]oct-3-en-2-one
• 4-hydroxy-3-{[2-(2-methoxy-ethoxy)methyl-6-(trifluoromethyl)-3-pyridinyl]carbonyl}bicyclo[3.2.1]oct-3-en-2-one
• rac-(1R,5R)-4-hydroxy-3-{2-[(2-methoxyethoxy)methyl]-6-(trifluoromethyl)pyridine-3-carbonyl}bicyclo[3.2.1]oct-3-en-2-one
• 4-hydroxy-3-{2-[(2-methoxyethoxy)methyl]-6-(trifluoromethyl)-3-pyridylcarbonyl}bicyclo[3.2.1]oct-3-en-2-one
• 4-Hydroxy-3-[1]naphthylmethyl-benzoesaeure
• 4-hydroxy-3-[1]naphthylmethyl-benzoic acid
• 4-hydroxy-3-[[2-[(2-methoxyethoxy)methyl]-6-(trifluoromethyl)-3-pyridinyl]carbonyl]bicyclo[3.2.1]oct-3-en-2-one
• 4-hydroxy-3-(2-methoxyethoxymethyl-6-trifluoromethyl-pyridin-3-yl-carbonyl)-bicyclo[3.2.1]oct-3-en-2-one
• 4-Hydroxy-3-({2-[(2-methoxyethoxy)methyl]-6-(trifluoromethyl)-3-p yridinyl}carbonyl)bicyclo[3.2.1]oct-3-en-2-one
• Benzoic acid,4-hydroxy-3-(1-naphthalenylmethyl)