二氟孕甾丁酯结构式
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常用名 | 二氟孕甾丁酯 | 英文名 | Difluprednate |
|---|---|---|---|---|
| CAS号 | 23674-86-4 | 分子量 | 508.552 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 600.3±55.0 °C at 760 mmHg | |
| 分子式 | C27H34F2O7 | 熔点 | 192 - 194ºC | |
| MSDS | 中文版 美版 | 闪点 | 316.9±31.5 °C |
二氟孕甾丁酯用途Difluprednate(Durezol)是一种皮质类固醇,可作用于术后眼睛疼痛和炎症。 |
| 中文名 | 二氟孕甾丁酯 |
|---|---|
| 英文名 | [(6S,8S,9R,10S,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-6,9-difluoro-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate |
| 中文别名 | 二氟泼尼酯 | 双氟泼尼酯 |
| 英文别名 | 更多 |
| 密度 | 1.3±0.1 g/cm3 |
|---|---|
| 沸点 | 600.3±55.0 °C at 760 mmHg |
| 熔点 | 192 - 194ºC |
| 分子式 | C27H34F2O7 |
| 分子量 | 508.552 |
| 闪点 | 316.9±31.5 °C |
| 精确质量 | 508.227264 |
| PSA | 106.97000 |
| LogP | 3.67 |
| 外观性状 | 固体;White to Light yellow powder to crystal |
| 蒸汽压 | 0.0±3.9 mmHg at 25°C |
| 折射率 | 1.545 |
| 储存条件 | 0-10°C;避免加热 |
| 水溶解性 | 水溶性：不溶；水溶解度：0.008 g/l ；可溶于：乙醇,甲醇,氯仿；极微溶：二乙醚 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危害码 (欧洲) | Xn |
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 2.0 |
| RTECS号 | TU3831500 |
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Topical cyclosporine a 1% for the treatment of chronic ocular surface inflammation.
Eye Contact Lens 40(5) , 283-8, (2014) To evaluate the use of topical cyclosporine A (CsA) 1% emulsion in the treatment of chronic ocular surface inflammation (OSI).We conducted a retrospective chart review of patients with various forms o... |
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Determination of natural and synthetic glucocorticoids in effluent of sewage treatment plants using ultrahigh performance liquid chromatography-tandem mass spectrometry.
Environ. Sci. Pollut. Res. Int. 22 , 14127-35, (2015) A sensitive and comprehensive analytical method for glucocorticoids (GCs) in water samples was developed and applied to effluent of sewage treatment plants (STPs). In the present study, totally 10 nat... |
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Pharmacokinetic features of difluprednate ophthalmic emulsion in rabbits as determined by glucocorticoid receptor-binding bioassay.
J. Ocul. Pharmacol. Ther. 27(1) , 29-34, (2011) Difluprednate (6α,9-difluoro-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate 17-butyrate, DFBA) has long been used as an anti-inflammatory dermatological agent. The main objectives of the c... |
| Butanoic acid, (6α,11β)-21-(acetyloxy)-6,9-difluoro-11-hydroxy-3,20-dioxopregna-1,4-dien-17-yl ester |
| Myser |
| Difluoroprednisolone butyrate acetate |
| (6α,11β)-21-Acetoxy-6,9-difluoro-11-hydroxy-3,20-dioxopregna-1,4-dien-17-yl butyrate |
| UNII-S8A06QG2QE |
| Difluprednate |
| 6a,9-Difluoro-11b,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-Acetate 17-Butyrate |
| (6a,11b)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione |
| 6α,9-Difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-butyrate |
| (6α,11β)-21-(acetyloxy)-6,9-difluoro-11-hydroxy-3,20-dioxopregna-1,4-dien-17-yl butanoate |
| 6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE |
| Durezol |
| 6a,9a-Difluoroprednisolone-21-acetate-17-butyrate |
| Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-, (6α,11β)- |
| DFBA |
| Epitopic |
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