L-threonolactone

更新时间:2024-02-01 17:10:11

L-threonolactone结构式
L-threonolactone结构式
品牌特惠专场
常用名 L-threonolactone 英文名 L-threonolactone
CAS号 21730-93-8 分子量 118.09
密度 0.99g/cm3 沸点 277.8ºC at 760mmHg
分子式 C4H6O4 熔点 N/A
MSDS 美版 闪点 101.3ºC

 L-threonolactone用途


L-苏氨酸内酯((3R,4S)-3,4-二羟基氧杂环戊烯-2-酮)是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。

 L-threonolactone名称

英文名 L-threonolactone
英文别名 更多

 L-threonolactone生物活性

描述 L-苏氨酸内酯((3R,4S)-3,4-二羟基氧杂环戊烯-2-酮)是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。
相关类别
参考文献

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 L-threonolactone物理化学性质

密度 0.99g/cm3
沸点 277.8ºC at 760mmHg
分子式 C4H6O4
分子量 118.09
闪点 101.3ºC
精确质量 118.02700
PSA 66.76000
蒸汽压 0.00443mmHg at 25°C
折射率 1.437

 L-threonolactone安全信息

危险品运输编码 NONH for all modes of transport
海关编码 2932209090

 L-threonolactone上下游产品

L-threonolactone上游产品  0

L-threonolactone下游产品  1

 L-threonolactone海关

海关编码 2932209090
中文概述 2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 L-threonolactone文献4

更多文献
A convenient preparation of aldonohydroxamic acids in water and crystal structure of L-erythronohydroxamic acid.

Carbohydr. Res. 335(3) , 195-204, (2001)

Hydroxamic acids derived from aldonic acids, namely aldonohydroxamic acids, have become an increasingly important class of inhibitors of enzymes involved in the metabolism of carbohydrates. We now rep...

Alkaline and smith degradation of oxidized dermatan sulphate-chondroitin sulphate copolymers.

Carbohydr. Res. 36(2) , 349-58, (1974)

Metabolism of l-Threonic Acid in Rumex x acutus L. and Pelargonium crispum (L.) L'Hér.

Plant Physiol. 69(6) , 1365-8, (1982)

l-Threonic acid is a natural constituent in leaves of Pelargonium crispum (L.) L'Hér (lemon geranium) and Rumex x acutus L. (sorrel). In both species, l-[(14)C]threonate is formed after feeding l-[U-(...

 L-threonolactone英文别名

2,3-dihydroxydihydrofuran-1-one
Threonolactone
di-TMS-Threono-1,4-lactone
(3R,4S)-3,4-Dihydroxydihydrofuran-2(3H)-one
L-threonic acid-4-lactone
threonic acid-1,4-lactone
L-treono-1,4-lactone
L-Threonic acid-1,4-lactone
(3R,4S)-3,4-dihydroxyoxolan-2-one
Bis-TMS-Threono-1,4-lactone
L-Threonsaeure-4-lacton
(3R,4S)-3,4-dihydroxy-dihydrofuran-2-one