22(R)-羟基胆固醇结构式
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常用名 | 22(R)-羟基胆固醇 | 英文名 | 22-alpha-Hydroxy Cholesterol |
|---|---|---|---|---|
| CAS号 | 17954-98-2 | 分子量 | 402.65 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 513.1±23.0 °C at 760 mmHg | |
| 分子式 | C27H46O2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 213.5±17.2 °C |
22(R)-羟基胆固醇用途22(R)-Hydroxycholesterol (Narthesterol) 是一种内源性的 LXR 激动剂。22(R)-Hydroxycholesterol (Narthesterol) 可用于丹吉尔病的研究。 |
| 中文名 | 22(R)-羟基胆固醇 |
|---|---|
| 英文名 | (22R)-22-hydroxycholesterol |
| 中文别名 | 22(r)-羟基胆甾醇 | 22-Alpha-羟基胆固醇 |
| 英文别名 | 更多 |
| 描述 | 22(R)-Hydroxycholesterol (Narthesterol) 是一种内源性的 LXR 激动剂。22(R)-Hydroxycholesterol (Narthesterol) 可用于丹吉尔病的研究。 |
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| 相关类别 | |
| 参考文献 |
| 密度 | 1.0±0.1 g/cm3 |
|---|---|
| 沸点 | 513.1±23.0 °C at 760 mmHg |
| 分子式 | C27H46O2 |
| 分子量 | 402.65 |
| 闪点 | 213.5±17.2 °C |
| 精确质量 | 402.349792 |
| PSA | 40.46000 |
| LogP | 7.66 |
| 蒸汽压 | 0.0±3.0 mmHg at 25°C |
| 折射率 | 1.536 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 危险品运输编码 | NONH for all modes of transport |
| 22(R)-羟基胆固醇上游产品 0 | |
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| 22(R)-羟基胆固醇下游产品 2 | |
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Oxysterols synergize with statins by inhibiting SREBP-2 in ovarian cancer cells.
Gynecol. Oncol. 135(2) , 333-41, (2014) Determine mechanisms responsible for enhanced statin efficacy in a novel statin combination we name STOX (STatin-OXysterol).Ovarian cancer cell lines were treated with combinations of statins and oxys... |
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HBCDD-induced sustained reduction in mitochondrial membrane potential, ATP and steroidogenesis in peripubertal rat Leydig cells.
Toxicol. Appl. Pharmacol. 282(1) , 20-9, (2015) Hexabromocyclododecane (HBCDD), a brominated flame retardant added to various consumer products, is a ubiquitous environmental contaminant. We have previously shown that 6-hour exposure to HBCDD distu... |
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Tumor necrosis factor alpha may act as an intraovarian mediator of luteinizing hormone-induced oocyte maturation in trout.
Biol. Reprod. 86(1) , 1-12, (2012) In fish, like in other vertebrates, luteinizing hormone (Lh) is an essential hormone for the completion of oocyte maturation. In salmonid fish (i.e., salmon and trout), oocyte maturation is induced by... |
| Narthesterol |
| 22BF-HYDROXYCHOLESTEROL |
| 22(S)-hydroxycholesterol |
| (3β,22S)-Cholest-5-ene-3,22-diol |
| 22BETA-HYDROXYCHOLESTEROL |
| Cholest-5-ene-3,22-diol, (3β,22S)- |
| 22R-OHC |
| 22(R)-HYDROXYCHOLESTEROL |
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