5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐

• 常用名: 5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐
• 英文名: Linsidomine hydrochloride
• CAS号: 16142-27-1
• 分子量: 206.630
• 密度: N/A
• 沸点: N/A
• 分子式: C₆H₁₁ClN₄O₂
• 熔点: 186 °C
• 闪点: N/A

5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐用途

SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation[1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion[2].

5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐名称

• 中文名: 5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐
• 英文名: 3-Morpholinosydnonimine hydrochloride
• 中文别名: 林西多明盐酸盐 | 5-氨基-3-(4-吗啉基)-1,2,3-二唑盐酸盐

5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐物理化学性质

• 熔点: 186 °C
• 分子式: C₆H₁₁ClN₄O₂
• 分子量: 206.630
• 精确质量: 206.057053
• PSA: 67.28000
• 外观性状: 白色针状或略淡黄色白色结晶粉末
• 储存条件: -20°C
• 水溶解性: soluble

5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐安全信息

• 安全声明 (欧洲): S24/25
• 海关编码: 2934999090

5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐制备

【方法一】
可用4-氨基吗啉先以氰化钾、甲醛氰甲基化，生成4-（氰甲基氨基）吗啉，然后以亚硝酸钠亚硝化得4-（氰甲基亚硝基氨基）吗啉，后者在盐酸甲醇中环合得到本品。

5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐英文别名

• 3-(4-morpholinyl)-5-sydnone imine hydrochloride
• [3-(4-Morpholinyl)-1,2,3-oxadiazol-3-ium-5-yl]azanide hydrochloride (1:1)
• 3-(4-Morpholinyl)sydnone imine hydrochloride Linsidomine hydrochloride SIN-1 hydrochloride
• T6N DOTJ A- AT5KNOYJ DUM &&sydnone
• SIN-I HYDROCHLORIDE
• LINSIDOMINE HCL
• 3-(4-morpholinyl)-sydnonimine hydrochloride
• [3-(Morpholin-4-yl)-1,2,3-oxadiazol-3-ium-5-yl]azanide hydrochloride (1:1)
• MFCD00221615
• 3-(4-Morpholinyl)sydnone imine hydrochloride
• LinsidoMine Chlorhydrate
• 3-morpholinosydnone imine hydrochloride
• 1,2,3-Oxadiazolium, 5-amino-3-(4-morpholinyl)-, inner salt, hydrochloride (1:1)
• MolsidoMine IMpurity A
• SIN-1
• SIN-1 CHLORIDE
• B-HT 933 dihydrochloride
• 3-morpholino-sydnonimine hydrochloride
• SIN-1 HCL
• 3-Morpholinosydnonimine hydrochloride
• 5-Imino-3-(morpholin-4-yl)-5H-1,2,3-oxadiazol-3-ium-2-ide hydrochloride (1:1)
• SIN-1 HYDROCHLORIDE
• EINECS 247-207-4
• LINSIDOMINE