N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯

• 常用名: N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯
• 英文名: Noopept
• CAS号: 157115-85-0
• 分子量: 318.368
• 密度: 1.2±0.1 g/cm3
• 沸点: 547.3±50.0 °C at 760 mmHg
• 分子式: C₁₇H₂₂N₂O₄
• 熔点: 94.0 to 98.0 °C
• 闪点: 284.8±30.1 °C

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯用途

Noopept (GVS-111)是可作为膳食补充剂的多肽。

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯名称

• 中文名: N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯
• 英文名: (S)-Ethyl 2-(1-(2-phenylacetyl)pyrrolidine-2-carboxamido)acetate
• 中文别名: 苯乙酰甘氨酸乙酯

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯生物活性

• 描述: Noopept (GVS-111)是可作为膳食补充剂的多肽。
• 相关类别:
  信号通路 >> 跨膜转运 >> iGluR
  信号通路 >> 神经信号通路 >> iGluR
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Firstova IuIu, et al. Studying specific effects of nootropic drugs on glutamate receptors in the rat brain. Eksp Klin Farmakol. 2011;74(1):6-10.

  [2]. Pelsman A, et al. GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons. Int J Dev Neurosci. 2003 May;21(3):117-24.

  [3]. Ostrovskaya RU, et al. Memory restoring and neuroprotective effects of the proline-containing dipeptide, GVS-111, in a photochemical stroke model. Behav Pharmacol. 1999 Sep;10(5):549-53.

  [4]. Gudasheva TA, et al. The major metabolite of dipeptide piracetam analogue GVS-111 in rat brain and its similarity to endogenous neuropeptide cyclo-L-prolylglycine. Eur J Drug Metab Pharmacokinet. 1997 Jul-Sep;22(3):245-52.

  [5]. Kovalenko LP, et al. Anti-inflammatory properties of noopept (dipeptide nootropic agent GVS-111). Eksp Klin Farmakol. 2002 Mar-Apr;65(2):53-5.

  [6]. Kovalenko LP, et al. Preclinical study of noopept toxicity. Eksp Klin Farmakol. 2002 Jan-Feb;65(1):62-4.

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 547.3±50.0 °C at 760 mmHg
• 熔点: 94.0 to 98.0 °C
• 分子式: C₁₇H₂₂N₂O₄
• 分子量: 318.368
• 闪点: 284.8±30.1 °C
• 精确质量: 318.157959
• PSA: 75.71000
• LogP: 1.28
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.549
• 储存条件: -20°C

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯安全信息

• 危险品运输编码: NONH for all modes of transport
• RTECS号: MC0814400
• 海关编码: 2942000000

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯英文别名

• Ethyl 1-(phenylacetyl)-L-prolylglycinate
• Glycine, 1-(2-phenylacetyl)-L-prolyl-, ethyl ester
• ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate
• Noopept
• N-phenylacetyl-L-prolylglycine ethyl ester
• GVS-111
• Nopept