Tigecycline hydrate

更新时间：2025-08-25 23:02:22

Tigecycline hydrate结构式	常用名	Tigecycline hydrate	英文名	Tigecycline hydrate
	CAS号	1229002-07-6	分子量	603.66400
	密度	N/A	沸点	N/A
	分子式	C₂₉H₃₉N₅O_8.xH₂O	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS07, GHS08	信号词	Danger

Tigecycline hydrate用途

虎环素是一种广谱甘氨酸环素类抗生素。虎环素水合物具有抑菌作用,通过与细菌的30S核糖体亚单位结合来抑制蛋白质合成,从而在原核翻译过程中阻止氨酰tRNA进入核糖体的A位点。虎环素水合物对革兰氏阳性菌和革兰氏阴性菌的耐药菌株具有活性。

英文名	(4S,4aS,5aR,12aR)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,hydrate
英文别名	更多

描述	虎环素是一种广谱甘氨酸环素类抗生素。虎环素水合物具有抑菌作用,通过与细菌的30S核糖体亚单位结合来抑制蛋白质合成,从而在原核翻译过程中阻止氨酰tRNA进入核糖体的A位点。虎环素水合物对革兰氏阳性菌和革兰氏阴性菌的耐药菌株具有活性。
相关类别	信号通路 >> 自噬 >> 自噬信号通路 >> 抗感染 >> 细菌

分子式	C₂₉H₃₉N₅O_8.xH₂O
分子量	603.66400
精确质量	603.29000
PSA	219.47000
LogP	2.48240

符号	GHS07, GHS08
信号词	Danger
危害声明	H319-H360
警示性声明	P201-P305 + P351 + P338-P308 + P313
危险品运输编码	NONH for all modes of transport
RTECS号	QI7619500

Tigecycline inhibits proliferation of Acanthamoeba castellanii.

Parasitol. Res. 114(3) , 1189-95, (2015)

Acanthamoeba is an opportunistic protozoan parasite responsible for different diseases in humans, such as granulomatous amoebic encephalitis and amoebic keratitis. Tigecycline, a third-generation tetr...

Novel drug combination for Mycobacterium abscessus disease therapy identified in a Drosophila infection model.

J. Antimicrob. Chemother. 69(6) , 1599-607, (2014)

Mycobacterium abscessus is known to be the most drug-resistant Mycobacterium and accounts for ∼80% of pulmonary infections caused by rapidly growing mycobacteria. This study reports a new Drosophila m...

Pharmacokinetics of intravenously administered tigecycline in eye compartments: an experimental study.

Graefes Arch. Clin. Exp. Ophthalmol. 252(12) , 1993-7, (2014)

The purpose of this study was to evaluate the ocular distribution of intravenously administered tigecycline in a rabbit uveitis model.Tigecycline, which has a broad spectrum of activity against many g...

Tigecyclin

9-t-Butylglycylamido-minocycline hydrate

Tigecycline hydrate