24R-卡泊三醇

• 常用名: 24R-卡泊三醇
• 英文名: 24R-Calcipotriol
• CAS号: 112827-99-3
• 分子量: 412.60500
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₄₀O₃
• 熔点: N/A
• 闪点: N/A

24R-卡泊三醇用途

24R-Calcipotriol(PRI 2202)是钙泊三醇的杂质,钙泊三醇是1,25-Dihydroxyvitamin D3类似物。

24R-卡泊三醇名称

• 中文名: 24R-卡泊三醇
• 英文名: 20(R)-(3'(R)-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-1(S),3(R)-dihydroxy-9,10-secopregna-5(Z),7(E),10(19)-triene

24R-卡泊三醇生物活性

• 描述: 24R-Calcipotriol(PRI 2202)是钙泊三醇的杂质,钙泊三醇是1,25-Dihydroxyvitamin D3类似物。
• 相关类别:
  信号通路 >> 维生素 D 相关 >> VD/VDR
  研究领域 >> 癌症
• 参考文献:

  [1]. Gocek, Elzbieta; Kielbinski, Marek; Baurska, Hanna et al. Different susceptibilities to 1,25-dihydroxyvitamin D3-induced differentiation of AML cells carrying various mutations. Leukemia Research (2010), 34(5), 649-657.

  [2]. Gocek, Elzbieta; Kielbinski, Marek; Wylob, Paulina et al. Side-chain modified vitamin D analogs induce rapid accumulation of VDR in the cell nuclei proportionately to their differentiation-inducing potential. Steroids (2008), 73(14), 1359-1366.

  [3]. Wietrzyk, Joanna; Nevozhay, Dmitry; Filip, Beata et al. The antitumor effect of lowered doses of cytostatics combined with new analogs of vitamin D in mice. Anticancer Research (2007), 27(5A), 3387-3398.

  [4]. Wietrzyk, Joanna; Chodynski, Michal; Fitak, Hanna et al. Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anti-Cancer Drugs (2007), 18(4), 447-457.

24R-卡泊三醇物理化学性质

• 分子式: C₂₇H₄₀O₃
• 分子量: 412.60500
• 精确质量: 412.29800
• PSA: 60.69000
• LogP: 5.09060
• 储存条件: 2-8℃

24R-卡泊三醇英文别名

• (24R)-Calcipotriene
• 24R-Calcipotriol
• 24-Epi-Calcipotriol