D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2结构式
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常用名 | D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 | 英文名 | H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 trifluoroacetate salt (Disulfide bond) |
|---|---|---|---|---|
| CAS号 | 103429-31-8 | 分子量 | 1062.26000 | |
| 密度 | 1.42g/cm3 | 沸点 | 1491.2ºC at 760mmHg | |
| 分子式 | C50H67N11O11S2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 855.7ºC |
用途CTOP 是一种多肽,可以作为 μ-opioid receptor 的拮抗剂。 |
| 中文名 | D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 |
|---|---|
| 英文名 | ctop |
| 英文别名 | 更多 |
| 密度 | 1.42g/cm3 |
|---|---|
| 沸点 | 1491.2ºC at 760mmHg |
| 分子式 | C50H67N11O11S2 |
| 分子量 | 1062.26000 |
| 闪点 | 855.7ºC |
| 精确质量 | 1061.45000 |
| PSA | 425.91000 |
| LogP | 3.30840 |
| 蒸汽压 | 0mmHg at 25°C |
| 折射率 | 1.68 |
| 储存条件 | -20°C,密闭,干燥 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 3 |
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D-PHE-CYS-TYR-D... 103429-31-8 |
| 文献:Journal of Medicinal Chemistry, , vol. 29, # 11 p. 2370 - 2375 |
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~%
D-PHE-CYS-TYR-D... 103429-31-8 |
| 文献:Journal of Medicinal Chemistry, , vol. 29, # 11 p. 2370 - 2375 |
|
~%
D-PHE-CYS-TYR-D... 103429-31-8 |
| 文献:Journal of Medicinal Chemistry, , vol. 29, # 11 p. 2370 - 2375 |
|
~%
D-PHE-CYS-TYR-D... 103429-31-8 |
| 文献:Journal of Medicinal Chemistry, , vol. 29, # 11 p. 2370 - 2375 |
| D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2上游产品 4 | |
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| D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2下游产品 0 | |
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Activation of mu or delta opioid receptors in the lumbosacral spinal cord is essential for ejaculatory reflexes in male rats.
PLoS ONE 10(3) , e0121130, (2015) Ejaculation is controlled by a spinal ejaculation generator located in the lumbosacral spinal cord, consisting in male rats of lumbar spinothalamic (LSt) cells and their inter-spinal projections to au... |
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Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
J. Neurosci. 35 , 9580-94, (2015) Due to its distinct pharmacological profile and lower incidence of adverse events compared with other opioids, buprenorphine is considered a safe option for pain and substitution therapy. However, des... |
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Synaptic upregulation and superadditive interaction of dopamine D2- and μ-opioid receptors after peripheral nerve injury.
Pain 155(12) , 2526-33, (2014) A sound strategy for improving the clinical efficacy of opioids involves exploiting positive interactions with drugs directed at other targets in pain pathways. The current study investigated the role... |
| DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL |
| NTB |
| D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-amide |
| M.W. 1062.26 C50H67N11O11S2 |
| D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 |
| CYS2,TYR3,ORN5,PEN7-AMIDE |
| threoninamide |
| D-Phe-Cys-Tyr-D-Trp-Orn-Pen-Thr-NH2 |
| [Cys2, Tyr3, Orn5, Pen7]-Somatostatin 14 (7-14), amide |