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4070-80-8生产厂家

4070-80-8价格

4070-80-8

4070-80-8结构式
4070-80-8结构式
  • 常用中文名:硬脂富马酸钠
  • 常用英文名:Sodium 2-octadecylfumarate
  • CAS号:4070-80-8
  • 分子式:C22H39NaO4
  • 分子量:390.53
  • 相关类别: 食品添加剂 面粉处理剂
  • 发布时间:2018-07-20 14:02:56
  • 更新时间:2024-01-02 08:27:05
  • 硬脂基富马酸钠可以用作赋形剂。药用辅料,或称药用辅料,是指除药物成分外,在制药过程中使用的其他化学物质。药用辅料一般是指药物制剂中的非活性成分,可以提高药物制剂的稳定性、溶解性和加工性。药用赋形剂还影响共同给药药物的吸收、分布、代谢和消除(ADME)过程[1]。

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中文名 硬脂富马酸钠
英文名 Sodium Stearyl Fumarate
中文别名 超级水亲润滑剂A
英文别名 2-Butenedioic acid, monooctadecyl ester, sodium salt, (2E)- (1:1)
Fumaric Acid Stearyl Ester Sodium Salt
Sodium (2E)-4-(octadecyloxy)-4-oxobut-2-enoate
(E)-2-Butenedioic acid monooctadecyl ester sodium salt Sodium octadecyl fumarate
Sodium (2E)-4-(octadecyloxy)-4-oxo-2-butenoate
Sodium Octadecyl Fumarate
Fumaric Acid Octadecyl Ester Sodium Salt
(E)-2-Butenedioic acid monooctadecyl ester sodium salt,Sodium octadecyl fumarate
Sodium stearyl fumarate
EINECS 223-781-1
描述 硬脂基富马酸钠可以用作赋形剂。药用辅料,或称药用辅料,是指除药物成分外,在制药过程中使用的其他化学物质。药用辅料一般是指药物制剂中的非活性成分,可以提高药物制剂的稳定性、溶解性和加工性。药用赋形剂还影响共同给药药物的吸收、分布、代谢和消除(ADME)过程[1]。
相关类别
参考文献

[1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

沸点 483.4ºC at 760mmHg
分子式 C22H39NaO4
分子量 390.53
闪点 153.5ºC
精确质量 390.274597
PSA 77.43000
LogP 5.39890
外观性状 固体;White to Light yellow powder to crystal
储存条件

避光,通风干燥处,密封保存

稳定性

常温常压下稳定,白色细粉。溶于甲醇,几乎不溶于水。

水溶解性 Practically insoluble in water, slightly soluble in methanol, practically insoluble in acetone and in anhydrous ethanol.
Sodium Stearyl Fumarate Revision number: 5
SAFETY DATA SHEET

Section1. IDENTIFICATION
Product name:Sodium Stearyl Fumarate

Revision number:5

Section2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDSNot classified
Not classified
HEALTH HAZARDS
ENVIRONMENTAL HAZARDSNot classified
GHS label elements, including precautionary statements
Pictograms or hazard symbolsNone
No signal word
Signal word
Hazard statementsNone
None
Precautionary statements:

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture:Substance
Components:Sodium Stearyl Fumarate
Percent:>98.0%(T)
CAS Number:4070-80-8
Synonyms:Fumaric Acid Stearyl Ester Sodium Salt , Sodium Octadecyl Fumarate , Fumaric Acid
Octadecyl Ester Sodium Salt
C22H39NaO4
Chemical Formula:

Section4. FIRST AID MEASURES
Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Skin contact:Remove/Take off immediately all contaminated clothing. Rinse skin with
water/shower. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth.
A rescuer should wear personal protective equipment, such as rubber gloves and air-
Protection of first-aiders:
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Suitable extinguishingDry chemical, foam, water spray, carbon dioxide.
media:
Sodium Stearyl Fumarate

Section5. FIRE-FIGHTING MEASURES
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Use personal protective equipment. Keep people away from and upwind of spill/leak.
Personal precautions,
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Handling is performed in a well ventilated place. Wear suitable protective equipment.
Technical measures:
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions:Keep container tightly closed. Store in a cool and dark place.
Store away from incompatible materials such as oxidizing agents.
Packaging material:Comply with laws.

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Install a closed system or local exhaust as possible so that workers should not be
Engineering controls:
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection:Protective gloves.
Eye protection:Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Solid
Form:Crystal- Powder
Colour:White - Slightly pale yellow
Odour:No data available
pH: No data available
Melting point/freezing point:No data available
No data available
Boiling point/range:
Flash point:No data available
Flammability or explosive
limits:
No data available
Lower:
Upper:No data available
No data available
Relative density:
Solubility(ies):
No data available
[Water]
[Other solvents]
Hot acetic acid
Soluble:
Sodium Stearyl Fumarate

Section10. STABILITY AND REACTIVITY
Chemical stability:Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide
products:

Section11. TOXICOLOGICAL INFORMATION
No data available
Acute Toxicity:
Skin corrosion/irritation: No data available
No data available
Serious eye
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC =No data available
NTP =No data available
No data available
Reproductive toxicity:

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
No data available
Fish:
Crustacea:No data available
Algae:No data available
Persistence / degradability: No data available
BioaccumulativeNo data available
potential(BCF):
Mobility in soil
Log Pow:No data available
No data available
Soil adsorption (Koc):
Henry's LawNo data available
constant(PaM3/mol):

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

Section14. TRANSPORT INFORMATION
Hazards Class:Does not correspond to the classification standard of the United Nations
Not listed
UN-No:

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.
Sodium Stearyl Fumarate


SECTION 16 - ADDITIONAL INFORMATION
N/A

生态学数据:

通常对水是不危害的,若无政府许可,勿将材料排入周围环境.

危害码 (欧洲) Xi
风险声明 (欧洲) 36/38
安全声明 (欧洲) 26
危险品运输编码 NONH for all modes of transport
海关编码 2917190090
海关编码 2917190090
中文概述 2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分
Summary 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%