467-13-0

• 常用中文名：可待因酮
• 常用英文名：Codeinone
• CAS号：467-13-0
• 分子式：C₁₈H₁₉NO₃
• 分子量：297.348
• 发布时间：2018-03-18 08:00:00
• 更新时间：2025-08-24 09:49:26

名称

• 中文名: 可待因酮
• 英文名: codeinone
• 英文别名: hydrocodone; (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one; (5α)-3-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-one; 6-Oxocodeine; EINECS 207-386-1; Morphinan-6-one, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α)-; dihydrocodeine; 6-Codeinone

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 466.9±45.0 °C at 760 mmHg
• 熔点: 182-183ºC
• 分子式: C₁₈H₁₉NO₃
• 分子量: 297.348
• 闪点: 236.1±28.7 °C
• 精确质量: 297.136505
• PSA: 38.77000
• LogP: 1.33
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.657

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QD2169000 CHEMICAL NAME : Morphinan-6-one, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl- CAS REGISTRY NUMBER : 467-13-0 BEILSTEIN REFERENCE NO. : 0094188 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C18-H19-N-O3 MOLECULAR WEIGHT : 297.38 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 11 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964

安全

• 风险声明 (欧洲): R22
• 危险品运输编码: UN 2811 6.1 / PGIII

合成路线

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