| 中文名 | 3-氨基三氮唑-5-羧酸 |
|---|---|
| 英文名 | 2-amino-3,4-dihydro-1H-naphthalene-2-carboxylic acid |
| 中文别名 |
2-氨基-1,2,3,4-四氢-2-萘羧酸
DL-2-氨基四氢萘-2-羧酸 |
| 英文别名 |
ATC
MFCD00800504 2-Amino-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid 2-aminotetralin-2-carboxylic acid 5-AMINO-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID 3-AMINO-5-CARBOXY-1,2,4-TRIAZOLE H-ATC-OH 2-Aminotetraline-2-carboxylicacid EINECS 222-868-1 |
| 熔点 | 303-313ºC |
|---|---|
| 分子式 | C11H13NO2 |
| 分子量 | 191.22600 |
| 精确质量 | 191.09500 |
| PSA | 63.32000 |
| LogP | 1.65770 |
| 储存条件 | Store at 0°C |
Synonym:None Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. The toxicological properties of this material have not been fully investigated. Skin: May cause skin irritation. The toxicological properties of this material have not been fully investigated. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 6331-63-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: > 300 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: N/A Explosion Limits, upper: N/A Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C11H13NO2 Molecular Weight: 191.23 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 6331-63-1 unlisted. LD50/LC50: Not available. Carcinogenicity: D,L-2-Aminotetralin-2-Carboxylic Acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 6331-63-1: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 6331-63-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 6331-63-1 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 安全声明 (欧洲) | 24/25 |
|---|
|
~94%
6331-63-1 |
| 文献：Liu, Bo; Liu, Gang; Nelson, Lisa T.J.; Patel, Jyoti R.; Sham, Hing L.; Xin, Zhili; Zhao, Hongyu Patent: US2005/14794 A1, 2005 ; Location in patent: Page 29 ; US 20050014794 A1 |
|
~55%
6331-63-1 |
| 文献：Grouiller; Nioche; Barailler; et al. European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 139 - 146 |
|
~98%
6331-63-1 |
| 文献：Cordi; Lacoste; Descombes; Courchay; Vanhoutte; Laubie; Verbeuren Journal of Medicinal Chemistry, 1995 , vol. 38, # 20 p. 4056 - 4069 |
|
~%
6331-63-1 |
| 文献：Journal of the American Pharmaceutical Association (1912-1977), , vol. 46, p. 118,122 |
|
~%
6331-63-1 |
| 文献：European Journal of Medicinal Chemistry, , vol. 15, # 2 p. 139 - 146 |
|
~%
6331-63-1 |
| 文献：Journal of Medicinal Chemistry, , vol. 38, # 20 p. 4056 - 4069 |
|
~%
6331-63-1 |
| 文献：European Journal of Medicinal Chemistry, , vol. 15, # 2 p. 139 - 146 |
| 上游产品 6 | |
|---|---|
| 下游产品 0 | |
