CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XY2300000
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CHEMICAL NAME :
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Triazene, 3,3-dimethyl-1-(m-pyridyl-N-oxide)-
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CAS REGISTRY NUMBER :
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21600-42-0
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LAST UPDATED :
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199709
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DATA ITEMS CITED :
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13
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MOLECULAR FORMULA :
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C7-H10-N4-O
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MOLECULAR WEIGHT :
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166.21
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WISWESSER LINE NOTATION :
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T6NJ AO CNUNN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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200 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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230 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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490 mg/kg/38W-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Brain and Coverings - tumors Peripheral Nerve and Sensation - peripheral nerve tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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540 mg/kg/36W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors
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TYPE OF TEST :
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Sex chromosome loss and nondisjunction
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TYPE OF TEST :
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Heritable translocation test
MUTATION DATA
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TYPE OF TEST :
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Host-mediated assay
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TEST SYSTEM :
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Rodent - mouse Yeast - Saccharomyces cerevisiae
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DOSE/DURATION :
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400 umol/kg
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REFERENCE :
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AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70- Volume(issue)/page/year: 3,99,1973
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