122965-41-7

• 常用中文名：6'-O-没食子酰芍药苷
• 常用英文名：6'-O-Galloyl paeoniflorin
• CAS号：122965-41-7
• 分子式：C₃₀H₃₂O₁₅
• 分子量：632.57
• 相关类别： 天然产物 萜类
• 发布时间：2018-10-17 15:44:57
• 更新时间：2025-08-26 16:04:58
• 没食子酸芍药苷是一种NF-κB抑制剂[1]。而没食子酸芍药苷是DNA断裂的抑制剂[2]。

名称

• 中文名: 没食子酰芍药苷
• 英文名: [(1R,2S,3R,5R,6R,8S)-6-Hydroxy-8-methyl-3-{[6-O-(3,4,5-trihydroxybenzoyl)-β-D-glucopyranosyl]oxy}-9,10-dioxatetracyclo[4.3.1.02,5.03,8]dec-2-yl]methyl benzoate
• 中文别名: 6'-O-没食子酰芍药甙
• 英文别名: [(1R,2S,3R,5R,6R,8S)-6-Hydroxy-8-methyl-3-{[6-O-(3,4,5-trihydroxybenzoyl)-β-D-glucopyranosyl]oxy}-9,10-dioxatetracyclo[4.3.1.0.0]dec-2-yl]methyl benzoate; ((2R,3S,4S,5R,6S)-6-(((1aR,1a¹S,2R,3aR,5S,5aR)-1a¹-((benzoyloxy)methyl)-2-hydroxy-5-methyltetrahydro-1H-3,4-dioxa-2,5-methanocyclobuta[cd]pentalen-5a(5H)-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl 3,4,5-trihydroxybenzoate; β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-(3,4,5-trihydroxybenzoate); Galloylpaeoniflorin; 6'-O-Galloyl paeoniflorin

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 887.7±65.0 °C at 760 mmHg
• 分子式: C₃₀H₃₂O₁₅
• 分子量: 632.57
• 闪点: 290.8±27.8 °C
• 精确质量: 632.17400
• PSA: 231.13000
• LogP: 4.89
• 外观性状: 粉末
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.735
• 储存条件: 2-8℃

生物活性

• 描述: 没食子酸芍药苷是一种NF-κB抑制剂[1]。而没食子酸芍药苷是DNA断裂的抑制剂[2]。
• 相关类别:
  研究领域 >> 其他
• 参考文献:

  [1]. Lu Y, Liu W, Zhang M, Deng Y, Jiang M, Bai G. The Screening Research of NF-κB Inhibitors from Moutan Cortex Based on Bioactivity-Integrated UPLC-Q/TOF-MS. Evid Based Complement Alternat Med. 2019;2019:6150357. Published 2019 Mar 3.

  [2]. OKUBO T., NAGAI F., USHIYAMA K., SETO T., SATOH K., KANO I.THE INHIBITORY EFFECTS OF MOUTAN CORTEX AND PAEONIAE ON RADIX ON OXIDATIVE DNA DAMAGE BY T-BUTYLHYDROQUINONE, PHENOLIC ANTIOXIDANT.Mutation Research, 1997.

安全

• 危害码 (欧洲): Xi