121346-32-5

• 常用中文名：SR 33805草酸盐
• 常用英文名：SR-33805
• CAS号：121346-32-5
• 分子式：C₃₄H₄₂N₂O₉S
• 分子量：654.77000
• 发布时间：2018-10-20 13:27:56
• 更新时间：2025-09-18 07:00:06
• SR-33805 is a calcium channel antagonist potentially for the treatment of atherosclerosis and heart failure. SR-33805 restored the MI-altered cell shortening without affecting the Ca(2+) transient amplitude, suggesting an increase of myofilament Ca(2+) sensitivity in MI myocytes. A SR33805-induced sensitization of myofilament activation was found to be associated with a slight increase in myosin light chain-2 phosphorylation and a more significant decrease on troponin I (TnI) phosphorylation. Decreased TnI phosphorylation was related to inhibition of protein kinase A activity by SR-33805.

名称

• 中文名: 3,4-二甲氧基-N-甲基-N-[3-[4-[[1-甲基-3-(1-甲基乙基)-1H-吲哚]磺酰基]苯氧基]丙基]苯乙胺乙酸盐
• 英文名: SR 33805 oxalate,3,4-Dimethoxy-N-methyl-N-[3-[4-[[1-methyl-3-(1-methylethyl)-1H-indol-2-yl]sulfonyl]phenoxy]propyl]benzeneethanamine

物化性质

• 沸点: 728.7ºC at 760 mmHg
• 分子式: C₃₄H₄₂N₂O₉S
• 分子量: 654.77000
• 闪点: 394.5ºC
• 精确质量: 654.26100
• PSA: 152.98000
• LogP: 6.33150
• 蒸汽压: 4.34E-21mmHg at 25°C
• 储存条件: 室温，干燥，密封

安全

• 危害码 (欧洲): Xi