25999-31-9

• 常用中文名：拉沙洛西
• 常用英文名：Lasalocid
• CAS号：25999-31-9
• 分子式：C₃₄H₅₄O₈
• 分子量：590.788
• 相关类别： 信号通路 抗感染 细菌
• 发布时间：2018-03-29 08:00:00
• 更新时间：2024-01-02 21:37:54
• Lasalocid是一种抗菌剂和抗球虫药, 用在饲料添加剂中。

名称

• 中文名: 那塞罗
• 英文名: Lasalocid
• 中文别名: 拉沙里菌素; 拉沙洛西
• 英文别名: 6-[(3R,4S,5S,7R)-7-{(2S,3S,5S)-5-Ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-3-methyltetrahydro-2-furanyl}-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic acid; lasalocid; Antibiotic X-537A; 3-Methyl-6-[7-ethyl-4-hydroxy-3,5-dimethyl-6-oxo-7-[5-ethyl-3-methyl-5-(5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2-tetrahydrofuryl]heptyl]salicylic Acid; D-galacto-Nonitol, 1,5:6,9-dianhydro-9-C-[(1R,3S,4S,5R)-7-(2-carboxy-3-hydroxy-4-methylphenyl)-1-ethyl-4-hydroxy-3,5-dimethyl-2-oxoheptyl]-3,4,7,8-tetradeoxy-2,6-di-C-ethyl-8-methyl-1-C-methyl-, (1S,9S)-; lasalic acid; (1S,9S)-1,5:6,9-Dianhydro-9-[(3R,5S,6S,7R)-9-(2-carboxy-3-hydroxy-4-methylphenyl)-6-hydroxy-5,7-dimethyl-4-oxononan-3-yl]-3,4,7,8-tetradeoxy-6-ethyl-2-C-ethyl-1,8-dimethyl-D-galacto-nonitol; Bovatec; Ionophore X-4537A; Benzoic acid, 6-((3R,4S,5S,7R)-7-((2S,3S,5S)-5-ethyl-5-((2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methyl; lasalocid acid

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 735.7±60.0 °C at 760 mmHg
• 分子式: C₃₄H₅₄O₈
• 分子量: 590.788
• 闪点: 224.8±26.4 °C
• 精确质量: 590.381897
• PSA: 133.52000
• LogP: 6.55
• 蒸汽压: 0.0±2.5 mmHg at 25°C
• 折射率: 1.529
• 储存条件: -20°C

生物活性

• 描述: Lasalocid是一种抗菌剂和抗球虫药, 用在饲料添加剂中。
• 相关类别:
  信号通路 >> 自噬 >> 自噬
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
  天然产物 >> 其他

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GP4000000 CHEMICAL NAME : 2,3-Cresotic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl -2H-pyran-2-yl) tetrahydro-3-methyl-2-furyl)-4-hydroxy-3,5-dimethyl-6 -oxononyl)-, (-)- CAS REGISTRY NUMBER : 25999-31-9 LAST UPDATED : 199706 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C34-H54-O8 MOLECULAR WEIGHT : 590.88 WISWESSER LINE NOTATION : T6OTJ B1 CQ C2 F- ET5OTJ BY2&VY1&YQY1&2R CQ D1 BVQ& C1 E2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 122 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 146 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,502,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 1,809,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 72 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - domestic DOSE/DURATION : 22 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984

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