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22855-57-8

22855-57-8结构式

常用中文名：溴琥胺
常用英文名：Brosuximide
CAS号：22855-57-8
分子式：C₁₀H₈BrNO₂
分子量：254.08000
发布时间：2018-05-30 08:00:00
更新时间：2024-02-01 18:59:57

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中文名	溴琥胺
英文名	3-(3-bromophenyl)pyrrolidine-2,5-dione
英文别名	3-(3-Bromophenyl)-2,5-pyrrolidinedione Brosuximide Brosuximida [INN-Spanish] 2-(m-Bromophenyl)succinimide Imid kwasu 3-bromofenylobursztynowego [Polish] 3-Bromophenylsuccinimide 3-(3-bromophenyl)-pyrrolidine-2,5-dione m-Bromophenylsuccinimide Succinimide,2-(m-bromophenyl) Brosuximidum [INN-Latin]

密度	1.606g/cm3
沸点	425.7ºC at 760mmHg
分子式	C₁₀H₈BrNO₂
分子量	254.08000
闪点	211.2ºC
精确质量	252.97400
PSA	49.66000
LogP	1.85510
蒸汽压	1.88E-07mmHg at 25°C
折射率	1.601

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WN2285000

CHEMICAL NAME :: Succinimide, 2-(m-bromophenyl)-

CAS REGISTRY NUMBER :: 22855-57-8

BEILSTEIN REFERENCE NO. :: 1457286

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H8-Br-N-O2

MOLECULAR WEIGHT :: 254.10

WISWESSER LINE NOTATION :: T5VMVTJ DR CE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 40,657,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 370 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 23,593,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 920 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 39,475,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,465,1978

海关编码	2925190090

海关编码	2925190090
中文概述	2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%